Oxygen and Hypoxia: New Aspects of a Central Problem


The most common types of chronic wounds share the problem of oxygen deficiency. In addition to the well-known consequences of macroangiopathy and (functional) microangiopathy, hypoxia is a common final phase for most types of chronic wounds. Therefore, it seems obvious that the restoration of oxygen should be a central part of successful wound therapy. Besides the recognised beneficial aspects of oxygenation, new findings have revealed the critical interaction between oxygen and reactive oxygen species, macrophages, and iron. Based on new pathophysiologic aspects and appropriate targeted diagnostics, numerous new treatment options can now be offered to patients. Hyperbaric oxygenation, normobaric/isobaric oxygen therapy, haemoglobin spray, oxygen-releasing wound dressings, and antioxidants/radical scavengers are examples of individualised therapy regimes for wound oxygenation

In this session various new aspects of pathophysiology, diagnostics, and therapy for the central problem of oxygen deficiency and hypoxia in different types of chronic wounds was introduced and critically discussed.


The session took place on Friday 16 May from 08.00-09.30 in room N103.